PRP is the abbreviation of Platelet Rich Plasma. PRP therapy offers a promising solution to accelerate healing of tendon injuries and osteoarthritis naturally without subjecting the patient to significant risk. PRP is an emerging treatment in a new health sector known as "Orthobiologics." The philosophy is to merge cutting edge technology with the body's natural ability to heal itself.

For 20 years, the application of autologous PRP has been safely used and documented in many fields including; orthopedics, sports medicine, dentistry, ENT, neurosurgery, ophthalmology, urology, wound healing, cosmetic, cardiothoracic, and maxillofacial surgery.

PRP therapy is used to mend injuries to tendons and ligaments without surgery. The procedure involves deriving concentrated platelets and white blood cells from a patient’s blood with the use of a closed platelet separator system and then mixing the PRP with activating agents for injection back into the patient’s own injured tissue. The injection causes a repair response from the body within the injured tissue. The repair response begins with the formation of a local blood clot in muscle, tendon, ligament, and bone followed by the dissolving of the implanted platelets. This releases growth factors that cause fibrous scar tissue to be formed, which results in injured tissue being replaced with healthy tissue.

Normally, blood contains plasma, red blood cells (RBC), white blood cells (WBC), and platelets. Typically a blood specimen contains 93% RBC, 6% Platelets, and 1% WBC. The rationale for PRP benefit lies in reversing the blood ratio by decreasing RBC to 5%, which are less useful in the healing process, and increasing platelets to 94% to stimulate recovery. Platelets are small discoid blood cells made in bone marrow with a lifespan of 7–10 days. Inside the platelets are many intracellular structures containing glycogen, lysosomes, and two types of granules. The alpha granules contain the clotting and growth factors that are eventually released in the healing process.

Platelet-Rich Plasma (PRP) has been utilized in aesthetic medicine (UK, Japan, and Asia, Europe) to rejuvenate and slow down the aging process and face (2006).
Science supports the use of PRP for the augmentation and regeneration of hard and soft tissues. PRP is the source of concentrated platelet content present in blood. Apart from assisting blood clotting, platelets also release growth factors that assist the human body to repair itself by stimulating cells to regenerate new tissue. Today, platelet rich plasma can easily be separated from blood, through a process of centrifugation. Using your enriched plasma permits the body to heal faster and more efficiently creating a network of collagen. Because your plasma (autologous) is used, there is no danger of disease transmission, anaphylaxis or neoplasia.

Platelets contain important growth factors that, when secreted, are responsible for:

• Tissue regeneration and rejuvenation
• increasing collagen production
• recruiting other cells to the site of injury
• initiating vascular in – growth
• inducing cell differentiation
• bone – mineralization
• extra cellular matrix formation
• Non – Allergenic
• It is a ‘body own’ physiological product vs. animal derived or human donor products.
• Elimination of donor transmissible infections
• Biological Glue: for tissue adhesion especially in skin flaps, bone grafts and trauma.

These are vital steps in collagen regeneration and wound healing.

Some application of PRP therapy in aesthetic treatment:

• Hair loss treatment
• Fine wrinkle removal
• Face & neck rejuvenation
• Acne scar treatment

Results are visible at 3 weeks and improve gradually over ensuing months with improvement in texture and tone. Laser, Mesoroller therapies can enhance the results.

There is very little chance for rejection or a negative allergic reaction because the injected substance is from the patient’s own body.

Persons with skin disease (SLE, porphyria, allergies), cancer, chemotherapy, severe metabolic and systemic disorders, and abnormal platelet function (i.e. blood disorders) are contraindications with PRP. Anti-coagulation therapy and underlying sepsis excludes the use of PRP.